Mg for Mg, Methandrostenolone is considered one of the strongest anabolic orals available to bodybuilders. It is important to note that some do suffer from estrogen related problems with the usage of Methandrostenolone, including bloat and sometimes "gyno" (the development of female tissue under the nipples in males resulting in unattractive and often painful lumps in this area). Because of this, bodybuilders may prefer to use an estrogen inhibitor such as Arimidex or Nolvadex while on this steroid. Like many other orals, Methandrostenolone is a C17-alpha alkylated compound, and therefore can be potentially toxic to the liver. It is recommended that bodybuilders using this anabolic also incorporate a liver protectant into their daily supplement regime, and that they keep their dosages of this powerful drug in reasonable range and try to limit cycle duration to 10 weeks or less. Methandrostenolone can make a great addition to any cycle, and is commonly stacked with all injectable steroids.