Renal parenchymal disease can be a cause or consequence of hypertension. Progressive renal damage is caused by the mechanical and humoral effects of glomerular hypertension. The renal damage decreases the kidneys' ability to excrete salt and excess fluid (resulting in a low renin state, as opposed to the high renin state found in renovascular hypertension), and the hypertension worsens. As renal damage progresses, hyperparathyroidism develops and erythropoietin production increases, exacerbating the hypertension. 5 , 18 Thus, a vicious cycle of worsening renal function and hypertension begins.
At least one studio made a conscious effort to keep its leading man squeaky clean. Before Cavill began his grueling five-month preproduction training for Steel , Warner Bros. requested a list of exactly what the training team might ask Cavill to use. Twight gladly complied, given that he believes radical body recomposition can be done naturally when it is guided by experienced trainers and driven by discipline and commitment. For Cavill, Twight recommended only Udo's Oil (a blend of essential fatty acids) and magnesium to aid sleep, the time when growth hormone occurs naturally.